The Great Osage Trail is a rail-trails project that runs for 9.2 miles, between Wellington and Oxford.

The trail corridor has been railbanked by the Sunflower Rail-Trails Conservancy.

The name of this trail pays homage to the historic Great Osage Trail, also known as the Osage Trace or the Kaw Trace, which was one of the more well-known Native American trails through Kansas.